What is Ultimum?

• A broad spectrum and long-acting horse wormer and boticide gel which contains the active ingredients moxidectin and praziquantel.
• Broad spectrum. Ultimum is indicated for the control of tapeworm and all important susceptible strains of gastrointestinal roundworms, including adult and encysted stages (DL, LL3, EL4) and benzimidazoleresistant strains of small strongyles, and aids in control of early encysted stages (EL3), including inhibited larvae.
• When used as directed, Ultimum is safe in foals over 4 weeks of age and in all breeding stock, including stallions and pregnant mares.
• Palatable and effective gel.
• Developed and made in Australia. Treats horses up to 700 kg.

Why Choose Ultimum?

• TIMELY – ULTIMUM^® is recommended for horses with a suspected large burden of encysted small strongyles (roundworms) typically in late Autumn or early Spring. It is also recommended for new horses arriving on a property with an unknown worming history.
• TARGETED – ULTIMUM^® is the ideal wormer for young and adult horses with a suspected large burden of encysted small strongyles. It is also recommended for new horses arriving on a property with an unknown worming history.
• POWERFUL – ULTIMUM^® contains moxidectin, a powerful and persistent second-generation ‘mectin’. When administered as part of Virbac’s Gold Standard strategic worming program, ULTIMUM^® provides horses effective and sustainable worm control in conjunction with EQUIMAX^®, EQUIMAX ELEVATION^® and STRATEGY-T^®. The Egg Reappearance Period (ERP) for ULTIMUM^® is at least 14 weeks, which means that recontamination of the pasture by strongyle eggs is significantly reduced during this period. It is important to note that resistance may develop to any chemical.
• Palatable – ULTIMUM^® is an oral gel and easy to administer.
• Developed and made in Australia. ULTIMUM^® is an Australian developed and manufactured product that is designed specifically for Australian conditions.

OXFENDAZOLE 100 g/L  White emulsion, relatively odourless and tasteless.

FARNAM® WORMA DRENCH®s effective against the following internal parasites:

Horses:

Mature & immature stages of Bloodworm (Strongylus vulgaris);
Large Strongyles or Redworms, including the migratory tissue stages of S. edentatus;
Large Roundworm,
Pinworms,
Small Redworms (Small strongyles or Cyathostome species susceptible to oxfendazole),
mature Stomach Worms (Habronema microstoma),
as well as the harmful migrating stages of the Bloodworm (S.vulgaris) (55-88% activity) with corresponding reduction in arterial lesions.

Cattle:    Dairy & Beef

Small Brown Stomach Worm (Ostertagia ostertagi) including inhibited fourth larval or hypobiotic stages,
Barber’s Pole Worm,
Small Intestinal Worm,
Stomach hairworm,
Thin Necked Intestinal Worm,
Hookworm,
Nodule Worm,
Lungworm, and
Cattle Tapeworm.

WORMA DRENCH in liquid form provides an economic and convenient method of controlling major internal Roundworms in horses on studs or in large groups, as well as Roundworms and Tapeworms in cattle on studs, dairy herds, feedlots and grazing stock.

DOSE AND ADMINISTRATION:
Administer orally with accurate drenching equipment, disposable syringe, stomach tube, or by mixing thoroughly into the feed. Base the dose on the heaviest animal in the herd. Calculate body weight using scales or a weigh-band.
MAY ALSO BE ADDED TO FEED

HORSES: Use 10 mL of WORMA DRENCH per 100 kg body weight or as per table
CATTLE: Use 5 mL of WORMA DRENCH

NOTE: Safe to use in pregnant, sick or debilitated animals, but always take care.

WITHHOLDING PERIODS:

(HORSES): MEAT: 28 days.

(CATTLE): MILK: NIL; MEAT: DO NOT ADMINISTER LESS THAN 8 DAYS BEFORE SLAUGHTER FOR HUMAN CONSUMPTION.

TRADE ADVICE: EXPORT SLAUGHTER INTERVAL (ESI): DO NOT USE less than 14 days before slaughter for export.

Active Constituent: 15.0g/L Deltamethrin

Dose Rates for Cattle: 5mL per 100kg liveweight.

The following table may be used as a guide.

Dose Rate for Horses: 5mL per 100kg liveweight.

The following table may be used as a guide.

Ultramax Equine (ivermectin and praziquantel) has been formulated for administration by oral drench or stomach tube (nasogastric intubation).  One low-volume dose is effective against important internal parasites, including tapeworms and the arterial stages of  Strongylus vulgaris, and bots.

Ivermectin is derived from the avermectins, a family of potent, broad-spectrum antiparasitic agents, which are isolated from fermentation of Streptomyces avermitilis.

Praziquantel is indicated for the treatment of tapeworms (Anoplocephala magna,  Paranoplecephala mamillana (adult, immature, heads, segments).

Mode of Action
Ivermectin is a member of the macrocyclic lactone class of endectocides which have a unique mode of action. Compounds of the class bind selectively and with high affnity to glutamate- gated chloride ion channels which occur in invertebrate nerve and muscle cells. This leads to an increase in the permeability of the cell membranes to chloride ions with hyperpolarization of the nerve or muscle cell, resulting in paralysis and death of the parasite.Compounds of this class may also interact with other ligand-gated chloride channels, such as those gated by the neurotransmitter gamma-aminobutyric acid (GABA).The margin of safety for compounds of this class is attributable to the fact that mammals do not have glutamate-gated chloride channels; the macrocylic lactones have a low affnity for other mammalian ligand-gated chloride channels and they do not readily cross the blood-brain barrier.
Praziquantel induces a rapid and sustained paralytic muscle contraction of the tapeworm parasite and tegumental disruption followed by expulsion of the parasite.

Indications:
Ultramax Equine when used at the recommended dose rate of 200µg ivermectin per kilogram liveweight and 1.5 mg/kg praziquantel controls the following parasites of horses:
Tapeworms:  Anoplocephala perfoliata, Anoplocephala magna, Paranoplacephala mamillana (adult, immature, heads, segments).
Large Strongyles: Strongylus vulgaris (adults and arterial larval stages), Strongylus edentatus (both adult and tissue stages), Strongylus equinus (Adults), Tridontophorus spp. (Adults), Craterostomum acuticaudatum (Adults)
Small Strongyles:  including benzimidazole resistant strains Cyathostomum spp. (Adults and fourth-stage larvae), Cylicocyclus spp. (Adults and fourth-stage larvae), Cylicostephanus spp. (Adults and fourth-stage larvae), Cylicodontophorus spp. (Adults and fourth-stage larvae), Gyalocephalus spp. (Adults and fourth-stage larvae), Coronocyclus spp. (Adults and fourth-stage larvae), Parapoteriostomum spp. (Adults and fourth-stage larvae), Petrovinema spp. (Adults and fourth-stage larvae), Poteriostomum spp. (Adults and fourth-stage larvae)
Pinworms:  Oxyuris equi (Adults and fourth-stage larvae)
Ascarids:  Parascaris equorum (Adults and fourth-stage larvae)
Bots:  Gasterophilus spp. (oral and gastric stages)
Hairworms:  Trichostrongylus axei (Adult)
Intestinal Threadworms:  Strongyloides westeri (adult)
Large Mouth Stomach Worms:  Habronema muscae (adult)
Lungworms:  Dictyocaulus arnfedi (adult and immature)
Ultramax Equine also controls skin lesions caused by cutaneous larvae of Habronema and Draschia spp. (summer sores), and Onchocerca spp., microflaraiae (cutaneous onchocerciasis)

Directions for Use:
SHAKE WELL BEFORE USE
The recommended dose is 1mL Ultramax Equine per 50kg liveweight (equivalent to 200µg ivermectin per kg liveweight and 1.5 mg praziquantel per kg liveweight).
Ultramax Equine can be given as an oral drench or by stomach tube (nasogastric intubation).  Nasogastric intubation should only be done by a veterinarian or under veterinary supervision.Administration by oral drench: For administration by this method, an undiluted dose is usually preferred.  Clear the horse’s mouth of any food material, elevate the horse’s head, andusing a suitable dosing syringe, deposit the appropriate dose in the back of the mouth.  In order to avoid unnecessary coughing or the potential for material to enter the trachea and lungs, do not use excessive pressure, do not use a large dose volume of diluted Ultramax Equine, and do not deposit the dose in the laryngeal area.  Increased dose rejection may occur if the dose is deposited in the front of the mouth.  Keep the horse’s head elevated and observe the horse to ensure the dose is swallowed.

Administration by stomach tube (gravity or positive fow): Drenching horses by nasogastric intubation requires specialised skills and knowledge.  Special consideration  should be given to the effects of potential for injury from handling, restraint and placement of the tube during administration by stomach tube.  Nasogastric intubation should only be done by a veterinarian or under veterinary supervision.

The recommended dose can be used diluted or undiluted up to approximately 40 times with clean tepid water.  Use tepid water to fush any drug remaining in the tube into the horse’s stomach.  Pour Ultramax Equine into a graduated cylinder for dose measurement.   Alternatively, use a calibrated dosing syringe inserted into the bottle to measure the appropriate dose.  Use a clean dry syringe if accessing the bottle to avoid contaminating the remaining product.
Discard any unused diluted Ultramax Equine suspension 24 hours after dilution.Develop a Regular Treatment Plan: All horses should be subject to regular worming to maintain good health and peak condition.  Particular attention should be given to young horses and mares.  Foals should be treated initially at 6 to 8 weeks of age and this treatment repeated regularly as required.  Frequency of treatment should be assessed by each property’s veterinary adviser considering the number of horses, their age distribution, reproductive status, stocking rate, grazing access, climate and property’s parasite infestation status.  Ultramax Equine is highly effective in the treatment and control of most types of equine helminths including tapeworms, gastrointestinal, cutaneous and pulmonary nematodes and bots of horses of any age.  With a regular treatment program the chances of verminous arteritis and colic caused by S. vulgaris will be reduced.Safety in Using: Ultramax Equine may be used both in young foals and very old animals.  Mares may be treated at any stage of pregnancy and fertility will not be affected in either sex.  Swelling and itching reactions after treatment with Ultramax Equine have occurred in horses carrying eavy infections of neck threadworm microflariae, Onchocerca sp.  These reactions were most likely the result of microflariae dying in large numbers.  Symptomatic treatment may be advisable.

Healing of summer sores involving extensive tissue changes may require other therapy in conjunction with Ultramax Equine.  Reinfection, and measures for its prevention should also be considered.
DO NOT USE IN ANIMALS OTHER THAN HORSES

MEAT WITHHOLDING PERIOD:  Do not use less than 28 days before slaughter for human consumption.

For control of synthetic pyrethroid susceptible Buffalo Fly (Haematobia irritans exigua) for up to 3 weeks and for control of Stable Fly (Stomoxys calcitrans) for up to 1 week on horses.

Provides protection from the Biting Midge (Culicoides brevitarsus) for at least 14 days with effective control of blood feeding C. brevitarsus for 6 days post treatment.

ACTIVE CONSTITUENT: 15.0g/L DELTAMETHRIN

Contraindications: This product is contraindicated for use on animals severely stressed or in ill health. This product should not be used on horse’s head forward of the ears. This product should not be applied as a single spot.

DOSE RATE FOR CATTLE: 5mL per 100kg liveweight

DOSE RATE FOR HORSES: 5mL per 100kg liveweight

WITHHOLDING PERIODS: Cattle: MEAT Zero (0) days; MILK Zero (0) days Horses: NOT TO BE USED on horses that may be slaughtered for human consumption.

Recommendations for use:

Equest® Plus Tape is palatable and effective for the treatment and control of:

Tapeworm: Anoplocephala perfoliata, Anoplocephala magna and Paranoplocephala mamillana.

Large Strongyles: Strongylus vulgaris (adults, L3 and L4 arterial stages), Strongylus edentatus (adults and L4 visceral larval stages), Strongylus equinus (adults), Triodontophorus spp. (adults) including T. brevicauda,

T. serratus and T. tenuicollis, Craterostomum acuticaudatum (adults).

Small Strongyles (adults): Cyathostomum spp. including C. catinatum and C. pateratum; Cylicostephanus spp. including C. calicatus, C. goldi; C. longibursatus and C. minutus, Cylicocyclus spp. including C. brevicapsulatus,

C. elongatus, C. insigne, C. leptostomum, C. nassatus, C. radiatus, C. ashworthi and C. ultrajectinus; Cylicodontophorus bicoronatus; Coronocyclus spp. including C. coronatus, C. labiatus and C. labratus; Gyalocephalus capitatus; Parapoteriostomum mettami; Peterovinema poculatus; Poteriostomum imparidentatum, as well as benzimidazole resistant strains.

Pinworms: Oxyurus equi (adults and L3/L4 larval stages). Ascarids: Parascaris equorum (adults and intestinal stages (L4)). Hairworms: Trichostrongylus axei (adults).

Intestinal Threadworms: Strongyloides westeri.

Large Mouthed Stomach Worms: Habronema spp. – gastric and cutaneous (summer sore) forms. Stomach Bots: Gasterophilus intestinalis (2 & 3 stage larvae), Gasterophilus nasalis (2 & 3 stage larvae). Cutaneous Onchocerciasis: Onchocerca spp. (microfiliariae).